David Lynch, the maverick American director who sustained a successful mainstream career while also probing the bizarre, the radical and the experimental, has died aged 78.

“It is with deep regret that we, his family, announce the passing of the man and the artist, David Lynch,” read a Facebook post. “We would appreciate some privacy at this time. There’s a big hole in the world now that he’s no longer with us. But, as he would say, “Keep your eye on the donut and not on the hole.” It’s a beautiful day with golden sunshine and blue skies all the way.”

Last August, Lynch said he had been diagnosed with emphysema and in November, spoke further about his breathing difficulties. “I can hardly walk across a room,” he said. “It’s like you’re walking around with a plastic bag around your head.”